Proteomic indicators of health relate to Alzheimer’s and neurodegenerative disease biomarkers

Journal article

H. E. Dark, Zhongsheng Peng, Michael R. Duggan, Gulzar N. Daya, Murat Bilgel, Y. An, A. Moghekar, S. Resnick, K. Walker
Alzheimer's & Dementia, 2022

Semantic Scholar DOI

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APA Click to copy
Dark, H. E., Peng, Z., Duggan, M. R., Daya, G. N., Bilgel, M., An, Y., … Walker, K. (2022). Proteomic indicators of health relate to Alzheimer’s and neurodegenerative disease biomarkers. Alzheimer's &Amp;Amp; Dementia.

Chicago/Turabian Click to copy
Dark, H. E., Zhongsheng Peng, Michael R. Duggan, Gulzar N. Daya, Murat Bilgel, Y. An, A. Moghekar, S. Resnick, and K. Walker. “Proteomic Indicators of Health Relate to Alzheimer’s and Neurodegenerative Disease Biomarkers.” Alzheimer's & Dementia (2022).

MLA Click to copy
Dark, H. E., et al. “Proteomic Indicators of Health Relate to Alzheimer’s and Neurodegenerative Disease Biomarkers.” Alzheimer's &Amp;Amp; Dementia, 2022.

BibTeX Click to copy

@article{h2022a,
  title = {Proteomic indicators of health relate to Alzheimer’s and neurodegenerative disease biomarkers},
  year = {2022},
  journal = {Alzheimer's &amp; Dementia},
  author = {Dark, H. E. and Peng, Zhongsheng and Duggan, Michael R. and Daya, Gulzar N. and Bilgel, Murat and An, Y. and Moghekar, A. and Resnick, S. and Walker, K.}
}

Abstract

Prior studies suggest that peripheral health and comorbid disease can influence Alzheimer’s disease (AD) pathology and neurodegenerative processes. However, no studies to date have comprehensively examined how measures of peripheral health and risk for non‐neurological disease relate to biomarkers commonly used in AD research. The present study examined the association between 16 protein‐based health indicators and plasma biomarkers of brain amyloid‐β (Aβ) accumulation, phosphorylated tau, neurodegeneration, and reactive astrogliosis.