MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging


Journal article


K. Walker, Michael R. Duggan, Zhaoyuan Gong, H. E. Dark, J. Laporte, M. Faulkner, Y. An, Alexandria Lewis, A. Moghekar, S. Resnick, M. Bouhrara
Annals of Clinical and Translational Neurology, 2023

Semantic Scholar DOI PubMedCentral PubMed
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APA   Click to copy
Walker, K., Duggan, M. R., Gong, Z., Dark, H. E., Laporte, J., Faulkner, M., … Bouhrara, M. (2023). MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging. Annals of Clinical and Translational Neurology.


Chicago/Turabian   Click to copy
Walker, K., Michael R. Duggan, Zhaoyuan Gong, H. E. Dark, J. Laporte, M. Faulkner, Y. An, et al. “MRI and Fluid Biomarkers Reveal Determinants of Myelin and Axonal Loss with Aging.” Annals of Clinical and Translational Neurology (2023).


MLA   Click to copy
Walker, K., et al. “MRI and Fluid Biomarkers Reveal Determinants of Myelin and Axonal Loss with Aging.” Annals of Clinical and Translational Neurology, 2023.


BibTeX   Click to copy

@article{k2023a,
  title = {MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging},
  year = {2023},
  journal = {Annals of Clinical and Translational Neurology},
  author = {Walker, K. and Duggan, Michael R. and Gong, Zhaoyuan and Dark, H. E. and Laporte, J. and Faulkner, M. and An, Y. and Lewis, Alexandria and Moghekar, A. and Resnick, S. and Bouhrara, M.}
}

Abstract

White matter damage is a feature of Alzheimer's disease, yet little is known about how facets of the Alzheimer's disease process relate to key features of white matter structure. We examined the association of Alzheimer's disease (Aß42/40 ratio; pTau181), neuronal injury (NfL), and reactive astrogliosis (GFAP) biomarkers with MRI measures of myelin content and axonal density.



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